NS, or Nephrotic Syndrome, is a kidney disorder characterized by a group of symptoms that occur due to increased permeability of the glomerular filtration barrier in the kidneys. This condition leads to abnormal leakage of large amounts of protein into the urine, resulting in low levels of protein in the blood and fluid retention in the body.
The treatment of NS focuses on managing symptoms, reducing protein leakage, controlling fluid retention, and addressing the underlying cause. The specific treatment approach may vary depending on the underlying cause and the individual patient's condition. A kidney biopsy is mandatory in the diagnosis and treatment, as a nephrotic syndrome can be because of several causes.
The treatment depends on the cause, the extent of damage on the biopsy, and the irreversibility of the biopsy. Common medications used are as follows:
- Corticosteroids
- Immunosuppressive agents
- Diuretics
- Dietary modifications
- Management of underlying conditions
- Supportive care
- Immunomodulatory therapies
- Targeted therapies.
