Frequently Asked Questions

Surgery plays a crucial role in the management of liver cancer, especially in cases where the tumour is localized and has not spread extensively. The specific surgical approach depends on factors such as the size and location of the tumour, Quality of Liver the overall health of the patient, and the extent of liver function. Some of the most common surgical options for the treatment of liver cancer include: Hepatectomy: It involves the surgical removal of a portion of the liver. The extent of the resection depends on the size and location of the tumour. The goal is to remove the cancerous tissue while preserving as much of the healthy liver as possible. Liver Transplantation: For certain patients with liver cancer, especially those with cirrhosis liver transplantation may be considered. In this procedure, the entire liver is replaced with a healthy liver from a deceased or living donor. Radiofrequency Ablation (RFA) and Microwave Ablation: These minimally invasive techniques involve the use of heat to destroy cancerous tissue. During RFA, a special needle is inserted into the tumour, and high frequency electrical currents generate heat, causing the tumour cells to be destroyed. Microwave ablation utilizes microwaves to achieve a similar result. These techniques are often employed for smaller tumours. Transarterial Chemoembolization (TACE): TACE involves injecting chemotherapy drugs directly into the blood vessels supplying the tumour, combined with blocking these vessels. This method helps to deliver high concentrations of chemotherapy to the tumour while limiting the blood supply.

Neonatal jaundice is a common condition in newborns and is caused by an excess of bilirubin, a yellow pigment produced during the breakdown of red blood cells. While it is a normal and often temporary occurrence, some infants may be at a higher risk of developing neonatal jaundice. Risk factors may include premature birth, blood type incompatibility of the mother and baby, suboptimal breastfeeding, birth trauma, infections, conditions like cephalohematoma (collection of blood between the baby's skull and periosteum) or history of a previous sibling with neonatal jaundice. Neonatal jaundice is a self-limiting condition. However, if bilirubin levels become excessively high, it can lead to a more severe form of jaundice called kernicterus, which can cause neurological damage. Treatment options may include phototherapy or, in severe cases, exchange transfusions. Parents should communicate any concerns about jaundice with their paediatrician for appropriate evaluation and management.

Choledochal cysts are congenital cystic dilations of the bile ducts, and they can pose a risk of complications such as infection, stone formation, and an increased likelihood of developing bile duct cancer. The standard and most common treatment for choledochal cysts involves the complete removal of the cyst. The affected portion of the bile duct is resected, and the remaining healthy bile duct is reconstructed to restore normal bile flow. After removing the cyst, the surgeon often performs a Roux-en-Y hepaticojejunostomy. This involves connecting the remaining bile duct to a loop of the small intestine (jejunum). This procedure allows the bile to flow from the liver into the intestine, bypassing the area where the cyst was located.

The Whipple procedure, also known as pancreaticoduodenectomy, is a complex surgical procedure used to treat tumours and other diseases affecting the pancreas, as well as adjacent organs such as the duodenum, bile duct, and sometimes part of the stomach. The surgery is named after American surgeon Dr. Allen Whipple, who first performed it in the 1930s. The Whipple procedure entails the excision of the pancreatic head, the duodenum, the gallbladder, and the bile duct. After removing these structures, the surgeon reconstructs the digestive tract to allow for the flow of digestive juices and bile into the small intestine. The remaining portion of the pancreas is then attached to the digestive tract. The Whipple procedure is a challenging surgery and is usually performed by experienced surgical teams. The goal is to remove the diseased tissue while preserving as much normal pancreatic and gastrointestinal function as possible. The procedure can be curative for some patients with pancreatic cancer or other localized diseases, but it requires careful postoperative management and long-term follow-up.

Liver transplantation is indicated when a person's liver is severely damaged or failing to the extent that it can no longer perform its essential functions. The most common reasons for a liver transplant include: End-stage liver disease Liver cancer Acute liver failure Biliary atresia and paediatric liver disease Metabolic liver diseases Severe liver damage due to chronic infections like hepatitis B or C

Split liver transplantation is a surgical procedure in which a single donor liver is divided into two separate grafts, which can then be transplanted into two different recipients. This technique aims to maximize the use of available donor organs and increase the number of liver transplants performed to more Patients in the view of limited Organ Availability. The liver is a unique organ with the ability to regenerate. This characteristic allows surgeons to split a donor liver into two parts: the larger portion, typically the right lobe, is transplanted into an adult recipient, while the smaller portion, usually the left lobe, is transplanted into a pediatric recipient or small size adult. Both portions of the liver will regenerate to near-normal size within a few weeks to months after transplantation.

There are mainly five types of liver cancer based upon the type of cell in the liver. Hepatocellular carcinoma (HCC) Hepatocellular carcinoma (HCC) is a common type of primary liver cancer which affects the main liver cells called hepatocytes. People with cirrhosis and men are more prone to get Hepatocellular Carcinoma. Fibrolamellar carcinoma Fibrolamellar carcinoma is rare liver cancer, it comes as a subtype of Hepatocellular carcinoma and usually seen in healthy teens and adults under 40 years old. Interestingly, people diagnosed as Fibrolamellar carcinoma is not usually associated with liver cirrhosis or Hepatitis B or C infection. Cholangiocarcinoma (bile duct cancer) Cholangiocarcinoma is a rare liver cancer of the bile ducts, also categorized under primary liver cancer. The carcinoma begins in the section of ducts inside the liver is called intrahepatic cholangiocarcinoma. Angiosarcoma Angiosarcoma a type of rare liver cancer affects the blood vessels of the liver; it is commonly seen in the elderly population. Angiosarcoma is also known as soft tissue sarcoma or haemangiosarcoma. Hepatoblastoma: Hepatoblastoma is a kind of rare primary liver cancer that mainly affects children under 3 years old.

Liver cancer is diagnosed by performing following tests and procedures; It is not possible to diagnose hepatic cancer by doing normal blood tests. A specific blood test is done to find levels of alfa-fetoprotein in serum (AFP). Increased levels of AFP indicate presence of liver cancer. Sometimes the doctor may suggest imaging studies such as a CT or MRI scan. Liver biopsy is another method used to identify malignant or benign tumour. It is done is by removing tissue from liver and examining under the microscope, liver biopsy can be done along with CT scan. Another method to identify liver cancer is by doing laparoscopy, in this procedure the surgeon assesses the signs of hepatocellular carcinoma by inserting a flexible tube with a camera and light at the tip (laparoscope) by making a small incision in the abdomen.

When it comes to prevention of liver cancer, it is really important to maintain a healthy lifestyle by doing regular exercise and following a balanced diet. Also, avoid hepatitis infection and exposure to cancer-causing substances such as aflatoxins, a toxin found on agricultural crops such as maize.

Most of the time the Signs and symptoms of liver cancer do not show up until the later stages, but sometimes the signs and symptoms may show up in the beginning stage. Listed below are the common symptoms of liver cancer of hepatic cancer: You may notice unplanned Weight loss, lack of appetite, nausea or vomiting and a feeling of fullness after having a small meal. Enlarged liver & spleen, pain in the right shoulder blade, abdominal pain and swelling Itching and Yellowing of the skin and eyes (jaundice) People with hepatic cancer may experience fever, enlarged veins on the belly that can be seen through the skin, and abnormal bruising or bleeding. Some signs and symptoms of hepatic cancer include increased blood calcium levels (hypercalcemia), Low blood sugar levels (hypoglycaemia) and high cholesterol levels