Leukemia

Leukemia is a malignant disorder of the blood and bone marrow characterized by the uncontrolled proliferation of abnormal white blood cells. According to Robbins & Cotran Pathologic Basis of Disease, leukemia is defined as a clonal disorder of hematopoietic cells characterized by excessive accumulation of immature or dysfunctional leukocytes in the blood and bone marrow.

Leukemia is classified into four major types:

1. Acute Lymphoblastic Leukemia (ALL)
2. Acute Myeloid Leukemia (AML)
3. Chronic Lymphocytic Leukemia (CLL)
4. Chronic Myeloid Leukemia (CML)

Clinical Features of Leukemia

General Symptoms

• Persistent Fatigue and Weakness – Due to anemia and decreased oxygen transport.
• Unexplained Fever and Night Sweats – Resulting from immune dysregulation and infection susceptibility.
• Unintentional Weight Loss – A hallmark of malignancies, reflecting metabolic alterations.

Hematological Manifestations

• Pallor – Indicative of anemia caused by reduced red blood cell production.
• Frequent Infections – Due to neutropenia and impaired immune defense.
• Easy Bruising and Bleeding – A consequence of thrombocytopenia, leading to petechiae, purpura, and prolonged bleeding.

Organ Involvement

• Bone Pain – Resulting from excessive leukemic cell proliferation in the bone marrow.
• Lymphadenopathy – Enlarged lymph nodes, especially in CLL and ALL.
• Hepatosplenomegaly – Due to leukemic infiltration of the liver and spleen.
• Flow Cytometry – Differentiates leukemia subtypes using surface markers.

Why Should You Choose Aster Hospitals?

Aster Hospitals provide advanced leukemia treatment through specialized clinics. They offer chemotherapy, targeted therapy, and supportive care with regular follow-ups. Their expert team includes oncologists, hematologists, and transplant specialists who ensure personalized treatment. Aster Hospitals follow international protocols and use cutting-edge technology for better outcomes. They also have dedicated bone marrow transplant units for severe cases. Patients receive holistic care, including nutritional and psychological support. Their facilities are well-equipped with modern diagnostic tools for accurate treatment planning. 

Why Choose a Leukemia Specialist?

A leukemia specialist ensures precise diagnosis, personalized treatment plans, and long-term follow-up to monitor relapse and manage treatment complications. Advanced diagnostic tools, targeted therapies, and multidisciplinary care significantly improve patient outcomes.