Dr. Charles Panackel

Dr. Charles Panackel is a Senior Consultant in Hepatology and Liver Transplantation with more than 15 years of experience in the Gastroenterology and Hepatology Department at Aster Medcity Hospital in Kochi. He is trained in advanced therapeutic endoscopy including, EUS and ERCP. Dr. Charles has vast experience in the care of pre-transplant and post-transplant patients.  His area of interest includes liver transplantation, viral hepatitis, fatty liver, cirrhosis, its complications, and liver cancer.
 

Fields of Special Interest

• Hepatology
• Fatty Liver
• Viral Hepatitis
• Cirrhosis Liver
• Liver Cancer
• Liver Transplantation

Educational Qualification

• MBBS Govt Medical College Kottayam 1997
• MD ( Internal Medicine) 2002 Govt Medical College Trivandrum
• DNB (Internal Medicine) 2005 NBE Delhi
• DM (Gastroenterology)2008 Govt Medical College Trivandrum
• Fellowship in Hepatology NUH Singapore 2015
• FRCP (Edhin) 2019

Work / Professional Experience 

• Senior Consultant in Hepatology and Liver Transplantation at Aster Medcity, Kochi since 2016. 
• Clinical Fellow in Hepatology NUH Singapore 2015
• Consultant in Gastroenterology and Hepatology at Medical Trust Hospital, Kochi from 2008 to 2015. 
• Visitor Observer in Liver Transplantation at Addenbrookes hospital, Cambridge in 2013.
• Senior Resident in Gastroenterology at Government Medical College Trivandrum from 2005 to 2008
• Senior Lecturer in Medicine at Government Medical College Kottayam from 2003 to 2005
• Senior Resident in Medicine at Government Medical College Trivandrum from 2000 to 2003
• Medical officer in Sunmary Clinic, Pala from 1998 to 2000 

Memberships and Fellowships

• Member National Academy of Medical Sciences, India (MNAMS) 2016
• Fellow Royal College of Physicians  (Edhinburg)
• Fellow of Indian Society of Gastroenterology 2022

Posts Held

1. Executive committee member Liver Transplantation Society of India 2020-22
2. Convener, Cochin Liver Club 2016 ongoing
   • Cochin liver club was started in 2016 and has its meetings once in every two months. Aim of the club is to keep the members updated on the recent advances in the field of Hepatology and Liver Transplantation
3. Convener, Cochin GUT Club 2011-2014
   • Cochin GUT Club is an association of Gastroenterologists and Gastrosurgeon in Cochin. It has 106 members. It takes care of the Academic and Professional Needs of Gastroenterologists and Gastrosurgeon in Cochin. Cochin GUT club hosts academic meetings once a month and an annual state conference every year.
4. Course Convener, LTSI Transplant Hepatology Course 2021
5. Convener LTSI Single theme meeting oh Intermediate stage HCC
6. Treasurer, Liver Transplant Society of India annual meeting 2019 Kochi
7. Organizing committee member for ISGCON national meet 2018 Kochi
8. Organizing Secretary, INASL single theme meeting on “Critically ill Liver Patient” 2017.
9. Organizing Secretary, Single theme meeting on “Hepatobiliary tumors” 2016.
10. Organizing Committee member for the 2011 International Association of Pancreatology Annual meet at Kochi
11. Organizing committee member for the 1st Therapeutic Endosonography workshop in the state in 2010 at Medical trust Kochi

Professional Memberships

• American Association for the study of liver disease (AASLD)
• European Association for the study of liver disease (EASL)
• International Liver Transplant Society (ILTS)
• Asia pacific association for the study of liver disease (APASL)
• International Liver Cancer Association
• Indian Medical Association (IMA)
• Association of Physicians of India (API_
• Indian Society of Gastroenterology (ISG)
• Liver transplantation society of India (LTSI)

Research Articles

Chapter in Books

1. Charles Panackel, Anish Philip, Ismail Siyad, Jacob M. Hepatitis B and Liver Transplantation. Text book of Liver Transplantation. 1st edition. Ed Chirag Desai, Paras Medical Publishers India 2021 (In Print).
2. Charles Panackel. Acute Liver Failure. Practical gastroenterology, 2nd Edition. Ed V Balakrishnan and G Rajesh, Jaypee Brothers Medical Publishers. 2016. India. ISBN: 9789352501908
3. Charles Panackel, Sunil K Mathai. Lower Gastrointestinal Bleed. In Principles and Practice of Geriatric Medicine. Ed OP Sharma, Viva Books Pvt Ltd, India (2015). ISBN 9788130934211

https://www.researchgate.net/profile/Charles-Panackel/publications

Articles 

1. Panackel C, Ganjoo N, Saif R, Jacob M. Decompensated Liver Disease: Liver Transplantation is the Best Option, Not the Last Option. IMA Kerala Medical Journal. 2016 Mar 30;9(1):17-27
2. Charles panackel, Rony Thomas, Benoy Sebastian, Sunil K Mathai. Recent advances in management of acute liver failure. Indian J Crit Care Med. 2015 Jan; 19(1): 27–33
3. Charles Panackel, Anish Philip, Ismail Siyad, Jacob M. Hepatitis B and Liver Transplantation. Text book of Liver Transplantation. 1st edition. Ed Chirag Desai, Paras Medical Publishers India 2021.
4. Charles Panackel. Acute Liver Failure. Practical gastroenterology, 2nd Edition. Ed V Balakrishnan and G Rajesh, Jaypee Brothers Medical Publishers. 2016. India. ISBN: 9789352501908
5. Charles Panackel, Sunil K Mathai. Lower Gastrointestinal Bleed. In Principles and Practice of Geriatric Medicine. Ed OP Sharma, Viva Books Pvt Ltd, India (2015). ISBN 9788130934211
6. Gupta S, Sudhindran S, Saraf N, Vijai A, Swaminathan S, Panackel C, Mehta NN, Varghese J, Singh S, Reddy MS, Viswanathan MS, Bhangui P, Mohanka R, Asthana S, Rohatgi S. Liver Transplant Society of India Guidelines for Liver Transplant during COVID-19 times. J Clin Exp Hepatol. 2021 Aug 20. doi: 10.1016/j.jceh.2021.08.012.
7. Reddy MS, Rajakumar A, Mathew JS, Venkatakrishnan L, Jothimani D, Sudhindran S, Jacob M, Narayanasamy K, Venugopal R, Mohanka R, Kaliamoorthy I, Varghese J, Panackel C, Mohamed Z, Vij M, Sachan D, Pillay VV, Saigal S, Dhiman R, Soin AS, Gupta S, Wendon J, Rela M, Sarin SK. Liver Transplantation Society of India Guidelines for the Management of Acute Liver Injury Secondary to Yellow Phosphorus-Containing Rodenticide Poisoning Using the Modified Delphi Technique of Consensus Development. J Clin Exp Hepatol. 2021 Jul-Aug;11(4):475-483.
8. Philip M, Augustine P, Thomas V, Ramesh GN, Vinayakumar KR, Ramachandran TM, Siyad I, Mukkada RJ, Devi RS, Chettupuzha AP, Panackel C et al. Multi-center prospective survey of inflammatory bowel diseases in Kerala: More than 2000 cases. Indian J Gastroenterol. 2017 Nov;36(6):459-467. 
9. Thomas R, Panackal C, John M, Joshi H, Mathai S, Kattickaran J, Iqbal M. Gastrointestinal complications in patients with chronic kidney disease--a 5-year retrospective study from a tertiary referral center. Ren Fail. 2013;35(1):49-55.
10. Gopalakrishnan D, Keyter M, Shenoy KT, Leena KB, Thayumanavan L, Thomas V, Vinayakumar K, Panackel C, Korah AT, Nair R, Kramvis A. Hepatitis B virus subgenotype A1 predominates in liver disease patients from Kerala, India. World J Gastroenterol. 2013 Dec 28;19(48):9294-306.
11. Medappil N, Jacob M, Lochan R, Asthana S, Reddy J, Saif R, Sandhyav R, Panackel C, Raja K, Sakpal M, Ganjoo N. Kasai portoenterostomy for biliary atresia - Surgical precautions for better outcomes. J Pediatr Surg. 2019 Apr;54(4):868-869. 
12. Rajiv Lochan, Rehan Saif, Naveen Ganjoo, Mallikarjun Sakpal, Charles Panackal, Kaiser Raja, Jayanth Reddy, Sonal Asthana, Mathew Jacob. Diaphragmatic herniation following donor hepatectomy for living donor liver transplantation: a serious complication not given due recognition. Ann Hepatobiliary Pancreat Surg. 2017 Nov; 21(4): 232–236.
13. Ramaswami PK, Joshi HV, Thomas R, Thomas R, Panackel C, Mathai SK. Diagnosis of an early stage IPSID using Syndecan 1. Trop Gastroenterol. 2014 Jul-Sep;35(3):195-6.
14. Charles Panackel, Harshad Joshy, Benoy Sebastian, Renu Thomas, Sunil K Mathai. Gastric antral polyps; A manifestation of portal hypertensive gastropathy. Indian J Gastroenterol (May–June 2013) 32(3):206–207
15. Panackel C, Benoy Sebastian, Mathai Sunil, Renu Mariam. Trichuris Dysentery Syndrome. Letter to editor. Annals of Tropical Medicine and Public Health 2011 4 (2) 148-149
16. Panackel C, Benoy Sebastian Mathai Sunil, Renu Mariam . Intestinal Spirochetosis. Letter to Editor. Indian J Pathol Microbiol 2010 53(4):902-903
17. Panackel C, Kumar A, Subhalal N, Krishnadas D, Kumar KRV. Hemosuccus pancreaticus complicating calcific chronic pancreatitis. J.Gastroenterol Hepatol 2007 Oct;22(10):1691
18. Panackel C, Arun T Korah, Devadas Krishnadas, Kumar KRV. Pancreatic pseudocyst presenting as dysphagia: A case report. Saudi Journal of Gastroenterology 2008 14(1):28-30
19. Panackel C, Joseph John, Devadas Krishnadas, Kumar KRV. Metastatic Crohns disease of External genitalia: A case report. Indian J Dermatol. 2008;53(3):146-8
20. Panackel C, Baiju, TR Radha, George Cherian. Ascites due to ovarian hyperstimulation syndrome: A case report and review of literature. Indian J Crit Care Med 2007 11(3) 155-60
21. Panackel C, Vishad, G Cherian, K Vijayakumar, RN Sharma. Eosinophilic meningitis due to Angiostrongylus cantonensis. Indian Journal of Medical Microbiology 2006 24(3):220-21
22. Panackel C, Malini, KC George, K Vijayakumar. Splenic abscess in a boy with Isolated Levocardia. JAPI 2005 july: 53:647-48
23. Pavithran K, Panackel C, Roy D, Thomas M. Chronic myeloid leukemia in a man with myasthenia gravis treated by thymectomy. Eur J Haematol 2002 Aug;69(2):105-107
24. Panackel C, Jacob M, Joe Francis, Kaiser Raja, Sakpal M, Naveen Ganjoo, Sonal Asthana, Rajiv Lochan. Diagnostic accuracy of non- invasive Methods (NFS Score and FIB-4) for detecting advanced fibrosis: A validation study of NFS score and FIB-4 in a cohort of South Indian patients with NAFLD. Journal of Hepatology, Vol. 70, Issue 1, e768: April 2019
25. Charles Panackel, Noushif M, Rommel S, Ganesh V, Geetha Philips, Anitta Francis, Brijesh Ray, GN Ramesh, Mathew Jacob. Epidemiology and Clinical Profile of Hepatocellular Carcinoma at a Tertiary Care Center in South India. JAPI February 2019 • VOL. 67
26. Charles Panackel, Bipi Prasannan, Mathew Jacob, Rommel Sandhyav, Noushif Medappil. Low volume plasma exchange (LVPE) in the management of acute liver failure (ALF): A case series. Hepatol Int (2019) 13 (Suppl 1):S1–S266
27. Fadl H. Veerankutty, Noushif Medappil, Rommel Sandhyav, Rajiv Lochan, Sonal Asthana, Jayanth Reddy, Rehan Saif, Charles Panackel. Preoperative Graft Weight Prediction Using Donor Biometrics in Living Donor Liver Transplantation: Are They Accurate? Journal of Clinical and Experimental Hepatology, Vol. 9, Issue 3, p443 May-June, 2019
28. Fadl H. Veerankutty, Anitta Francis, S. Rommel, M. Noushif, Charles Panackel, Mathew Jacob. Liver Transplantation in Alcoholic Liver Disease: Does It Impact on Socioeconomic Parameters? Journal of Clinical and Experimental Hepatology, May-June, 2019 Vol. 9, Issue3, p43817.
29. Is pre-operative biliary imaging mandatory in all living liver donor assessment? A prospective study N Medappil, J Reddy, R Saif, B Ray, C Panackal, K Raja, M Sakpal TRANSPLANTATION 102, 232-232
30. Charles Panackel, Joe Francis, S Rommel, M Noushif, Mathew Jacob, Jeffey George, Ismail Siyad, G N Ramesh. Validation study of non-alcoholic fatty liver disease (NAFLD) fibrosis score (NFS) for non-invasive diagnosis of fibrosis in NAFLD in South Indian population. Indian J Gastroenterol (November 2018) 37(Suppl 1):A85
31. Charles Panackel, Snija Balan, S Rommel, M Noushif, Mathew Jacob, Jeffey George, Ismail Siyad, Brijesh Ray, G N Ramesh. Prevalence, risk factors and prognostic significance of sarcopenia in liver cirrhosis in Indian population. Indian J Gastroenterol (November 2018) 37(Suppl 1):A86
32. Panackel C, Noushif Ahmed, Rommel S, Rajeev Lochan, Sonal Asthana, Kaiser Raja, Naveen Ganju, Rehan Saif. Non-alcoholic fatty liver disease in non-obese South Indians – data from living liver donors. Journal of Clinical and Experimental Hepatology, Vol. 8, S50
33. N Toke, Thomas R, Panackel C, Sebastian B, Mathai S. Microbiological Profile of Spontaneous Bacterial Peritonitis in Patients with Liver Cirrhosis in South India Clinical Gastroenterology and Hepatology 2017;15(1):157
34. Charles Panackel. Epidemiology and Clinical profile of Inflammatory Bowel Disease in South India. Conference: APDW 2015: Journal of Gastroenterology and Hepatology 2015; 30 (Suppl. 4): 111
35. Thwin Maung Aye, Charles Panackel, Boon Leng Kieron Lim, poh Seng Tan, How Cheng Low, Yin Mei Lee, Yock Young Dan, Seng Gee Lim, Guan Huei Lee. 30day Mortality Assessment By CLIF-SOFA and MELD in Patients With Acute on Chronic Liver Failure from Hepatitis B Flare. Transplantation  July 2015; 99:7S(1) -145
36. P. Kakkadasam Ramaswami · H. Joshi · N. Toke · C. Panackel ·S. Mathai · Role of interferon gamma release assay (IGRA) in differentiating gastrointestinal tuberculosis from Crohn's disease. Journal of Crohn’s and Colitis 02/2014; 8:S123
37. R. Thomas · P. Kakkadasam Ramaswami · H. Joshi · N. Toke · C. Panackel · S. Mathai. Role of endoscopic biopsy in distinguishing between Crohn's disease and intestinal tuberculosis. ·Journal of Crohn’s and Colitis 02/2014; 8:S122-S123. C. 
38. C.Panackel, P.K.Ramaswami, R. Thomas, B. Sebastian, R.M. Thomas, S. Mathai. Differentiating Crohn’s disease from Intestinal Tuberculosis in a Tuberculosis endemic area. United European Gastroenterology Journal 2014 2(1S); A 211C. 
39. Panackel C, P. Ramaswami, H. Joshy, R. Thomas, B. Sebastian, S. Mathai. Utility of an Interferon Gamma release assay, TBFERON Gold (TBG) in diagnosing Ileocolonic Tuberculosis. United European Gastroenterology Journal 2014 2(1S); A 211
40. Panackel C, Ramesh M, Krishnadas D, Subhalal N, KRV Kumar. J Four cases of Obscure gastrointestinal bleed in chronic calcific pancreatitis. Gastroenterol Hepatol 2006 A43
41. R Pradeep, V J Harshad, N T Nilesh, Rony Thomas, Charles Panackel, Sunil K Mathai. Diagnostic utility of EUS guided FNAC of mediastinal lymphadenopathy K Indian J Gastroenterol (November 2013) 32(Suppl 1)A131
42. Harshad Vinay Joshi , Pradeep Kakkadasam Ramaswami, Nilesh Toke, Sunil Mathai, Charles Panackel, Rony Thomas. Percutaneous endoscopic gastrostomy (PEG): A single centre experience Indian J Gastroenterol (November 2013) 32(Suppl 1):A121
43. Harshad Vinay Joshi , Pradeep Kakkadasam Ramaswami, Nilesh Toke, Sunil K Mathai, Charles Panackel, Rony Thomas.Renal resistive index and its utility in cirrhotic patients Indian J Gastroenterol (November 2013) 32(Suppl 1):A81
44. Charles Panackel, Harshad Joshy, K R Pradeep, Benoy Sebastian, Sunil K Mathai. Epidemiology of upper gastrointestinal bleed in a tertiary care center. Indian J Gastroenterol (November 2011) 30(Suppl 1):A102
45. Charles Panackel, Rajech NA, Benoy Sebastian, Sunil K Mathai.  Clinical profile of eosinophilic gastroenteritis in Kerala..Indian J Gastroenterol (2010) 29 (Suppl 1):A93
46. Panackel C, T Joseph, Krishnadas D, Kumar KRV. Risk factors for short term mortality in alcoholic hepatitis. Indian Journal of Gastroenterology 2008 vol 27 (suppl 1) March S22
47. Thomas Joseph, Panackel C, Krishnadas D, KRV Kumar. Value of hepatic venous wave forms in predicting varices. Indian Journal of Gastroenterology 2008 vol 27(suppl 1) March; S7
48. Panackel C, Thomas Joseph, Arun T Korah, Joseph John, Krishnadas D, KRV Kumar. Spectrum of Colonic mucosal changes in cirrhotic and noncirrhotic portal hypertension. Indian Journal of Gastroenterology 2007 vol26(suppl 2) Nov: A59-A60
49. Panackel C, Thomas Joseph, Arun T Korah, D Krishnadas, KRV Kumar. Spontaneous bacterial peritonitis, clinical spectrum and prognostic factors. Indian Journal of Gastroenterology 2007 vol26(suppl 2) Nov :A87-A88
50. Arun T Korah, Panackel C, Krishnadas D, KRV Kumar. Prevalence of eosinophilic esophagitis in patients with esophageal symptoms. Indian Journal of Gastroenterology 2007 vol 26 (suppl 2) Nov: A18-A19 
51. Panackel C, Thomas Joseph, Arun T Korah, Joseph John, Krishnadas D, KRV Kumar. Demographic and clinical profile of acute hepatitis A in a tertiary care centre in Kerala. INASL 2007
52. Panackel C, Ramesh M, Krishnadas D, Shenoy KT, KRV Kumar. Prevalence of helicobacter pylori infection in patients with gastric cancer in south India. Indian journal of Gastroenterology 2006 Nov ;Vol 25 (Suppl 2): A30